The Mars 500 facility. releasing the cosmonauts required a can opener.
At the time of this writing, the 6 virtual cosmonauts of the Mars 500 project have tasted the freedom of being back on Earth, or at least out of isolation, for just over three hours. Congrats to them and all of their hard work. Personally, I don't like going more than a few days without getting out of house, so staying put for a year and a half is definitely an epic win in my book.